BDBM50523143 CHEMBL4542919

SMILES CCOC(=O)CNC(=O)C(N(C(=O)C#C)c1ccc(OC)cc1OC)c1cccs1

InChI Key InChIKey=AHOOZADJPNUFOQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50523143   

TargetProtein disulfide-isomerase(Human)
National Taiwan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50523143BDBM50523143(CHEMBL4542919 | US12605353, Compound C5)
Affinity DataIC50: 1.00E+4nMAssay Description:Covalent inhibition of PDI (unknown origin) by insulin aggregation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetProtein disulfide-isomerase(Human)
National Taiwan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50523143BDBM50523143(CHEMBL4542919 | US12605353, Compound C5)
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PDI expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in enzyme-mediated bov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 50523143BDBM50523143(CHEMBL4542919 | US12605353, Compound C5)
Affinity DataIC50: 7.60E+5nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent