BDBM50523598 CHEMBL4530290

SMILES OC(=O)C[C@H]1CC[C@H](CC1)Oc1ccc(cn1)-c1ccc(cn1)-c1nc2cc(cnc2[nH]1)C(F)(F)F

InChI Key InChIKey=UNWXUCUCEFLFIK-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50523598   

TargetDiacylglycerol O-acyltransferase 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50523598(CHEMBL4530290)
Affinity DataIC50: 7nMAssay Description:Inhibition of human DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50523598(CHEMBL4530290)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50523598(CHEMBL4530290)
Affinity DataIC50: 970nMAssay Description:Activity against human A2AR assessed as inhibition of cAMP accumulation by cAMP functional assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50523598(CHEMBL4530290)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human ACAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandPNGBDBM50523598(CHEMBL4530290)
Affinity DataKi:  2.34E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed