BDBM50523606 CHEMBL4461166

SMILES OC(=O)C[C@H]1CC[C@@H](CC1)OC1CCN(CC1)c1ccc(cn1)-c1nc2c(F)cccc2[nH]1

InChI Key InChIKey=LVXCTBHTIRUVQQ-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50523606   

TargetDiacylglycerol O-acyltransferase 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50523606(CHEMBL4461166)
Affinity DataIC50: 8nMAssay Description:Inhibition of human DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50523606(CHEMBL4461166)
Affinity DataIC50: 21nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50523606(CHEMBL4461166)
Affinity DataIC50: 910nMAssay Description:Activity against human A2AR assessed as inhibition of cAMP accumulation by cAMP functional assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50523606(CHEMBL4461166)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ACAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandPNGBDBM50523606(CHEMBL4461166)
Affinity DataKi:  1.07E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed