BDBM50524181 CHEMBL4459225

SMILES COc1cc(\C=C\C(=O)OCCCCCCN(C)CCCCOC(=O)c2c3ccccc3cc3ccccc23)cc(OC)c1OC

InChI Key InChIKey=UIMZRNVDDIWWPP-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50524181   

TargetATP-dependent translocase ABCB1(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50524181(CHEMBL4459225)
Affinity DataEC50:  520nMAssay Description:Inhibition of P-glycoprotein (unknown origin) in MDCK-MDR1 assessed as inhibtion of calcein-AM transport incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandPNGBDBM50524181(CHEMBL4459225)
Affinity DataEC50:  3.80E+3nMAssay Description:Inhibition of BCRP (unknown origin) in MDCK-MDR1 assessed as inhibtion of hoechst 33342 transport incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed