BDBM50524239 CHEMBL4469780

SMILES OC(c1ccc(c(F)c1)-c1ccc(NC(=O)Cc2ccc(cc2)[N+]([O-])=O)cc1)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=UMANBUHWIZGPIR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50524239   

TargetNuclear receptor ROR-gamma(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50524239(CHEMBL4469780 | US12297164, Example 3)
Affinity DataIC50: 1.49E+3nMAssay Description:Inverse agonist activity at Gal4-fused RORgamma LBD (unknown origin) expressed in 293T cells measured after 24 hrs by dual-luciferase reporter gene a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50524239(CHEMBL4469780 | US12297164, Example 3)
Affinity DataIC50: 1.49E+3nMAssay Description:Table 1: Experimental materials: target protein RORγ with the final concentration of 200 nM; experimental buffer (10×) MOPS (500 mM) PH 7.4, CHAPS (0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50524239(CHEMBL4469780 | US12297164, Example 3)
Affinity DataIC50: 4.85E+3nMAssay Description:Table 1: Experimental materials: target protein RORγ with the final concentration of 200 nM; experimental buffer (10×) MOPS (500 mM) PH 7.4, CHAPS (0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent