BDBM50524274 CHEMBL4532449

SMILES [#6]-[#6](-[#6])-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6]-[#7]-1-[#6]-[#6]-[#8]-[#6]-[#6]-1)-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#6](=O)[C@@]1([#6]-[#8][Si;v4](c2ccccc2)(c2ccccc2)C([#6])([#6])[#6])[#6]-[#8]1

InChI Key InChIKey=HOSSAEKKJNDWLK-LKPKVSIJSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50524274   

TargetProteasome subunit beta type-5(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50524274(CHEMBL4532449)
Affinity DataIC50:  112nMAssay Description:Inhibition of 20S proteasome beta5 subunit in human RPMI8226 cell lysate using Suc-LLVY-AMC as substrate pretreated for 1 hr followed by substrate ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed