BDBM50524367 CHEMBL4580450
SMILES CC1CCCc2c1nc(N)nc2-c1cccc(Br)c1
InChI Key InChIKey=OTJUQNSTENJDMP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50524367
TargetHistamine H2 receptor(Homo sapiens (Human))
Academy of Scientific and Innovative Research (Acsir)
Curated by ChEMBL
Academy of Scientific and Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataEC50: 840nMAssay Description:Agonist activity at recombinant human Gs-coupled H2 receptor expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulat...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Academy of Scientific and Innovative Research (Acsir)
Curated by ChEMBL
Academy of Scientific and Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: 85nMAssay Description:Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
Academy of Scientific and Innovative Research (Acsir)
Curated by ChEMBL
Academy of Scientific and Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataEC50: 840nMAssay Description:Agonist activity at recombinant human Gs-coupled H2 receptor expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulat...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Academy of Scientific and Innovative Research (Acsir)
Curated by ChEMBL
Academy of Scientific and Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...More data for this Ligand-Target Pair