BDBM50527060 CHEMBL4461958

SMILES [H][C@@]12COc3cnc4cc(c(Cl)cc4c3N1C[C@H](C)N(C2)C(=O)C=C)-c1c(O)cccc1F

InChI Key InChIKey=YZSYFOAFNHPZBJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50527060   

TargetGTPase KRas(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50527060(CHEMBL4461958)
Affinity DataIC50: 7.65E+3nMAssay Description:Inhibition of GDP bound biotinylated human C-terminal Avi/His6-tagged KRAS G12C mutant (1 to 166 residues) expressed in Escherichia coli BL21 (DE3) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed