BDBM50527068 CHEBI:17734::CHEMBL468766

SMILES C/C(O)=C1\C(=O)[C@@H]2[C@H]3c4c[nH]c5cccc(c45)C[C@H]3C(C)(C)N2C1=O

InChI Key InChIKey=CNZIQHGDUXRUJS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50527068   

TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 3(Human)
University of Chemistry and Technology Prague

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50527068BDBM50527068(CHEMBL468766 | CHEBI:17734)
Affinity DataIC50: 90nMAssay Description:Inhibition of human SERCA3a expressed in COS7 cells microsomal membranes preincubated for 10 mins followed by addition of ATP and measured after 40 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 2(Human)
University of Chemistry and Technology Prague

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50527068BDBM50527068(CHEMBL468766 | CHEBI:17734)
Affinity DataIC50: 90nMAssay Description:Inhibition of human SERCA2b expressed in COS7 cells microsomal membranes preincubated for 10 mins followed by addition of ATP and measured after 40 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Rabbit)
University of Chemistry and Technology Prague

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50527068BDBM50527068(CHEMBL468766 | CHEBI:17734)
Affinity DataIC50: 90nMAssay Description:Inhibition of rabbit SERCA1b expressed in COS7 cells microsomal membranes preincubated for 10 mins followed by addition of ATP and measured after 40 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed