BDBM50527338 CHEMBL4475957::US10829446, Compound 54

SMILES Fc1ccc(cc1C(=O)NNS(=O)(=O)c1ccccc1)-c1ncccn1

InChI Key InChIKey=QSBBVGXUWABZDC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50527338   

TargetHistone acetyltransferase KAT6A [507-778](Human)
Monash University

US Patent
LigandChemical structure of BindingDB Monomer ID 50527338BDBM50527338(CHEMBL4475957 | US10829446, Compound 54)
Affinity DataIC50: 137nMAssay Description:Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A [507-778](Human)
Monash University

US Patent
LigandChemical structure of BindingDB Monomer ID 50527338BDBM50527338(CHEMBL4475957 | US10829446, Compound 54)
Affinity DataIC50: 140nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed