BDBM50527598 CHEMBL4303293

SMILES Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(N)=O)c1nnc(C)n1-2

InChI Key InChIKey=QECMENZMDBOLDR-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50527598   

TargetBromodomain-containing protein 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50527598BDBM50527598(CHEMBL4303293)
Affinity DataIC50: 92nMAssay Description:Inhibition of BRD4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetDelta and Notch-like epidermal growth factor-related receptor(Human)
Knight Cancer Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50527598BDBM50527598(CHEMBL4303293)
Affinity DataIC50: 142nMAssay Description:Inhibition of BET in bortezomib Resistant human RPMI-8226 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous one...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDelta and Notch-like epidermal growth factor-related receptor(Human)
Knight Cancer Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50527598BDBM50527598(CHEMBL4303293)
Affinity DataIC50: 196nMAssay Description:Inhibition of BET in Melphalan Resistant human RPMI-8226 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous one ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDelta and Notch-like epidermal growth factor-related receptor(Human)
Knight Cancer Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50527598BDBM50527598(CHEMBL4303293)
Affinity DataIC50: 310nMAssay Description:Inhibition of BET in human bortezomib-resistant ANBL6 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous one sol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDelta and Notch-like epidermal growth factor-related receptor(Human)
Knight Cancer Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50527598BDBM50527598(CHEMBL4303293)
Affinity DataIC50: 458nMAssay Description:Inhibition of BET in human RPMI-8226 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous one solution cell prolif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDelta and Notch-like epidermal growth factor-related receptor(Human)
Knight Cancer Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50527598BDBM50527598(CHEMBL4303293)
Affinity DataIC50: 647nMAssay Description:Inhibition of BET in human U-266 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous one solution cell proliferat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDelta and Notch-like epidermal growth factor-related receptor(Human)
Knight Cancer Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50527598BDBM50527598(CHEMBL4303293)
Affinity DataIC50: 6.92E+3nMAssay Description:Inhibition of BET in human ANBL-6 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous one solution cell prolifera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed