BDBM50528072 CHEMBL4474673::US11634404, Compound 43

SMILES COc1ccc(OCCN2CCN(CC2)C(=O)c2ccncc2)cc1

InChI Key InChIKey=IEITXWDJKKGTIY-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50528072   

TargetD(3) dopamine receptor(Human)
The United States of America, As Represented By The Secretary, Department of Health and Human Services

US Patent
LigandPNGBDBM50528072(CHEMBL4474673 | US11634404, Compound 43)
Affinity DataEC50:  2.20E+4nMAssay Description:Compounds were tested for their ability to compete with the orthosteric radioligand [3H]methylspiperone for binding to the D3 DAR using stable HEK ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent

TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50528072(CHEMBL4474673 | US11634404, Compound 43)
Affinity DataEC50:  2.20E+4nMAssay Description:Agonist activity at human D3R expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 90 mins by beta-galactosidas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed