BDBM50529565 CHEMBL4438313

SMILES Oc1cn2CCN(Cc3ccccc3)Cc2cc1=O

InChI Key InChIKey=KAPWGNWNAIAKFF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50529565   

TargetLanosterol synthase(Rat)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50529565(CHEMBL4438313)
Affinity DataIC50: 220nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50529565(CHEMBL4438313)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged S-COMT expressed in 293-6E cells using 7,8-dihydroxy-4-methylcoumarin as substrate and SAM as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed