BDBM50529638 CHEMBL4566534

SMILES C[C@H](NC(=O)C1=C(C)c2ccccc2C1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(=O)[C@@]1(C)CO1

InChI Key InChIKey=ADBUEVSHEJICCM-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50529638   

TargetProteasome subunit beta type-8(Human)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529638(CHEMBL4566534)
Affinity DataIC50: 38nMAssay Description:Inhibition of LMP7 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-8(Human)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529638(CHEMBL4566534)
Affinity DataIC50: 38nMAssay Description:Inhibition of LMP7 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Mouse)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529638(CHEMBL4566534)
Affinity DataIC50: 47nMAssay Description:Inhibition of 20S proteosome beta 5 in mouse A20 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Mouse)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529638(CHEMBL4566534)
Affinity DataIC50: 47nMAssay Description:Inhibition of 20S proteosome beta 5 in mouse A20 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-8(Mouse)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529638(CHEMBL4566534)
Affinity DataIC50: 50nMAssay Description:Inhibition of LMP7 in mouse A20 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-8(Mouse)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529638(CHEMBL4566534)
Affinity DataIC50: 50nMAssay Description:Inhibition of LMP7 in mouse A20 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529638(CHEMBL4566534)
Affinity DataIC50: 54nMAssay Description:Inhibition of 20S proteosome beta 5 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529638(CHEMBL4566534)
Affinity DataIC50: 54nMAssay Description:Inhibition of 20S proteosome beta 5 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed