BDBM50530962 CHEMBL4441937

SMILES COc1ccc(c(F)c1)-c1cc(nc(N)n1)N(Cc1ccccn1)Cc1ccccn1

InChI Key InChIKey=CTKGVRLKMSOBAN-UHFFFAOYSA-N

Data  2 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50530962   

TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego

Curated by ChEMBL
LigandPNGBDBM50530962(CHEMBL4441937)
Affinity DataEC50:  110nMAssay Description:Agonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as increase in channel currents at -60 mV holding potential by tw...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego

Curated by ChEMBL
LigandPNGBDBM50530962(CHEMBL4441937)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego

Curated by ChEMBL
LigandPNGBDBM50530962(CHEMBL4441937)
Affinity DataEC50:  110nMAssay Description:Agonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as increase in channel currents at -60 mV holding potential by tw...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego

Curated by ChEMBL
LigandPNGBDBM50530962(CHEMBL4441937)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego

Curated by ChEMBL
LigandPNGBDBM50530962(CHEMBL4441937)
Affinity DataIC50:  470nMAssay Description:Inhibition of human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as decrease in ACh-induced channel currents at -60 mV holding potential...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego

Curated by ChEMBL
LigandPNGBDBM50530962(CHEMBL4441937)
Affinity DataIC50:  470nMAssay Description:Inhibition of human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as decrease in ACh-induced channel currents at -60 mV holding potential...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed