BDBM50531956 CHEMBL4533911

SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc2Oc3c(ccc4cc(ccc34)-c3cnc([nH]3)[C@@H]3CCCN3C(=O)[C@@H](NC(=O)OC)C(C)C)C(C)c2c1

InChI Key InChIKey=BPLXIAPCPXUWBZ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50531956   

TargetNonstructural protein 5A(Hepacivirus C)
Merck

Curated by ChEMBL
LigandPNGBDBM50531956(CHEMBL4533911)
Affinity DataEC50:  0.00570nMAssay Description:Inhibition of NS5A in HCV genotype 1a assessed as decrease in viral replicationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Merck

Curated by ChEMBL
LigandPNGBDBM50531956(CHEMBL4533911)
Affinity DataEC50:  49nMAssay Description:Inhibition of NS5A Y93H mutant in HCV genotype 1a assessed as decrease in viral replicationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed