BDBM50532192 CHEMBL4451717

SMILES COc1cc(ccc1OCc1ccc(cc1)C1CC1)C1CN(C1)C(=O)c1cc(COCC(CO)(CO)CO)ccn1

InChI Key InChIKey=OBKPWSDOCBHIBP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50532192   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50532192(CHEMBL4451717)
Affinity DataIC50: 20nMAssay Description:Inhibition of human CSF1R tyrosine kinase domain (538 to 972 residues) using Poly(Glu, Tyr)-biotinylated peptide as substrate preincubated for 5 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50532192(CHEMBL4451717)
Affinity DataIC50: 28nMAssay Description:Inhibition of CSF1R in CSF1-induced DBA/1J mouse BMMC assessed as reduction in LPS-induced IL6 production preincubated for overnight followed by LPS-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed