BDBM50532196 CHEMBL4586087

SMILES CCc1ccc(COc2ccc(cc2OC)C2CN(C2)C(=O)c2cc(OCCN3CCN(C)CC3)ccn2)cc1

InChI Key InChIKey=IPTAYBOCGZIFMP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50532196   

TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50532196(CHEMBL4586087)
Affinity DataIC50: 37nMAssay Description:Inhibition of CSF1R in CSF1-induced DBA/1J mouse BMMC assessed as reduction in LPS-induced IL6 production preincubated for overnight followed by LPS-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50532196(CHEMBL4586087)
Affinity DataIC50: 53nMAssay Description:Inhibition of human CSF1R tyrosine kinase domain (538 to 972 residues) using Poly(Glu, Tyr)-biotinylated peptide as substrate preincubated for 5 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed