BDBM50532579 CHEMBL4451582

SMILES COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCC(=O)Nc1ccccc1C(C)C)N1CCOCC1

InChI Key InChIKey=MHDALBFWKOEXAK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50532579   

TargetEndothelin-1 receptor(RAT)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50532579(CHEMBL4451582)
Affinity DataIC50:  63nMAssay Description:Displacement of 125I-ET1 from ETA receptor in rat A7R5 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Sus scrofa)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50532579(CHEMBL4451582)
Affinity DataIC50:  0.860nMAssay Description:Displacement of 125I-ET1 from pig ETB receptor transfected in grivet COS7 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50532579(CHEMBL4451582)
Affinity DataIC50:  63nMAssay Description:Displacement of 125I-ET1 from ETA receptor in rat A7R5 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Sus scrofa)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50532579(CHEMBL4451582)
Affinity DataIC50:  0.860nMAssay Description:Displacement of 125I-ET1 from pig ETB receptor transfected in grivet COS7 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed