BDBM50532618 CHEMBL4435709

SMILES CNc1nccc(n1)N1CC[C@@H](C1)NC(=O)Nc1ccc(OC)cc1

InChI Key InChIKey=RYHFXCAVTJQSKW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50532618   

TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532618(CHEMBL4435709)
Affinity DataIC50: 7.16E+3nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532618(CHEMBL4435709)
Affinity DataIC50: 7.16E+3nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed