BDBM50532620 CHEMBL4440347

SMILES FC(F)(F)c1cc(NC(=O)N[C@H]2CCN(C2)c2ccc3nncn3n2)ccc1Cl

InChI Key InChIKey=XJFPWEGWVPIYIH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50532620   

TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532620(CHEMBL4440347)
Affinity DataIC50: 4.20nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532620(CHEMBL4440347)
Affinity DataIC50: 4.20nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed