BDBM50532847 CHEMBL4529463

SMILES CC1(C)CC(=O)c2c(C1)nc1n(Cc3ccccc3)cc(C#N)c1c2-c1ccccc1

InChI Key InChIKey=QRAZJRNLKMFUIK-UHFFFAOYSA-N

Data  18 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50532847   

TargetReverse transcriptase(Human immunodeficiency virus type 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50532847(CHEMBL4529463)
Affinity DataIC50: 730nMAssay Description:Inhibition of HIV1 RT using A5'-end 32P-labeled 24-mer primer/a48-mer template preincubated for 5 mins followed by 25 uM nucleotides addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50532847(CHEMBL4529463)
Affinity DataIC50: 730nMAssay Description:Inhibition of HIV1 RT using 17-mer DNA/Alexa Fluor 488 5'-end labeled DNA/Alexa Fluor 555-aha-dUTP as primer/template/substrate preincubated for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50532847(CHEMBL4529463)
Affinity DataIC50: 730nMAssay Description:Inhibition of HIV1 RT using A5'-end 32P-labeled 24-mer primer/a48-mer template preincubated for 5 mins followed by 25 uM nucleotides addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50532847(CHEMBL4529463)
Affinity DataIC50: 730nMAssay Description:Inhibition of HIV1 RT using 17-mer DNA/Alexa Fluor 488 5'-end labeled DNA/Alexa Fluor 555-aha-dUTP as primer/template/substrate preincubated for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50532847(CHEMBL4529463)
Affinity DataIC50: 960nMAssay Description:Inhibition of HIV1 RT using A5'-end 32P-labeled 24-mer primer/a48-mer template preincubated for 5 mins followed by 10 uM nucleotides addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50532847(CHEMBL4529463)
Affinity DataIC50: 960nMAssay Description:Inhibition of HIV1 RT using A5'-end 32P-labeled 24-mer primer/a48-mer template preincubated for 5 mins followed by 10 uM nucleotides addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50532847(CHEMBL4529463)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of HIV1 RT Y181C mutant using 17-mer DNA/Alexa Fluor 488 5'-end labeled DNA/Alexa Fluor 555-aha-dUTP as primer/template/substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50532847(CHEMBL4529463)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of HIV1 RT Y181C mutant using 17-mer DNA/Alexa Fluor 488 5'-end labeled DNA/Alexa Fluor 555-aha-dUTP as primer/template/substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50532847(CHEMBL4529463)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of HIV1 RT using A5'-end 32P-labeled 24-mer primer/a48-mer template preincubated for 5 mins followed by 1 uM nucleotides addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50532847(CHEMBL4529463)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of HIV1 RT using A5'-end 32P-labeled 24-mer primer/a48-mer template preincubated for 5 mins followed by 1 uM nucleotides addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50532847(CHEMBL4529463)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of HIV1 RT K103N mutant using 17-mer DNA/Alexa Fluor 488 5'-end labeled DNA/Alexa Fluor 555-aha-dUTP as primer/template/substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50532847(CHEMBL4529463)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of HIV1 RT K103N mutant using 17-mer DNA/Alexa Fluor 488 5'-end labeled DNA/Alexa Fluor 555-aha-dUTP as primer/template/substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50532847(CHEMBL4529463)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HIV1 RT using A5'-end 32P-labeled 24-mer primer/a48-mer template preincubated for 5 mins followed by 0.5 uM nucleotides addition measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50532847(CHEMBL4529463)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HIV1 RT using A5'-end 32P-labeled 24-mer primer/a48-mer template preincubated for 5 mins followed by 0.5 uM nucleotides addition measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50532847(CHEMBL4529463)
Affinity DataIC50: 6.90E+4nMAssay Description:Inhibition of HIV1 RT E138K using 17-mer DNA/Alexa Fluor 488 5'-end labeled DNA/Alexa Fluor 555-aha-dUTP as primer/template/substrate preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50532847(CHEMBL4529463)
Affinity DataIC50: 6.90E+4nMAssay Description:Inhibition of HIV1 RT E138K using 17-mer DNA/Alexa Fluor 488 5'-end labeled DNA/Alexa Fluor 555-aha-dUTP as primer/template/substrate preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50532847(CHEMBL4529463)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HIV1 RT V108I mutant using 17-mer DNA/Alexa Fluor 488 5'-end labeled DNA/Alexa Fluor 555-aha-dUTP as primer/template/substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50532847(CHEMBL4529463)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HIV1 RT V108I mutant using 17-mer DNA/Alexa Fluor 488 5'-end labeled DNA/Alexa Fluor 555-aha-dUTP as primer/template/substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed