BDBM50532848 CHEMBL4443785

SMILES CC(=O)c1c(C)nc2n(Cc3ccccc3)cc(C#N)c2c1-c1ccc(cc1)[N+]([O-])=O

InChI Key InChIKey=IULKTCFQVAEFOA-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50532848   

TargetReverse transcriptase(Human immunodeficiency virus type 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50532848(CHEMBL4443785)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of HIV1 RT using 17-mer DNA/Alexa Fluor 488 5'-end labeled DNA/Alexa Fluor 555-aha-dUTP as primer/template/substrate preincubated for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50532848(CHEMBL4443785)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of HIV1 RT using 17-mer DNA/Alexa Fluor 488 5'-end labeled DNA/Alexa Fluor 555-aha-dUTP as primer/template/substrate preincubated for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50532848(CHEMBL4443785)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of HIV1 RT K103N mutant using 17-mer DNA/Alexa Fluor 488 5'-end labeled DNA/Alexa Fluor 555-aha-dUTP as primer/template/substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50532848(CHEMBL4443785)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of HIV1 RT K103N mutant using 17-mer DNA/Alexa Fluor 488 5'-end labeled DNA/Alexa Fluor 555-aha-dUTP as primer/template/substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50532848(CHEMBL4443785)
Affinity DataIC50: 5.90E+4nMAssay Description:Inhibition of HIV1 RT E138K using 17-mer DNA/Alexa Fluor 488 5'-end labeled DNA/Alexa Fluor 555-aha-dUTP as primer/template/substrate preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50532848(CHEMBL4443785)
Affinity DataIC50: 5.90E+4nMAssay Description:Inhibition of HIV1 RT E138K using 17-mer DNA/Alexa Fluor 488 5'-end labeled DNA/Alexa Fluor 555-aha-dUTP as primer/template/substrate preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50532848(CHEMBL4443785)
Affinity DataIC50: 7.80E+4nMAssay Description:Inhibition of HIV1 RT Y181C mutant using 17-mer DNA/Alexa Fluor 488 5'-end labeled DNA/Alexa Fluor 555-aha-dUTP as primer/template/substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50532848(CHEMBL4443785)
Affinity DataIC50: 7.80E+4nMAssay Description:Inhibition of HIV1 RT Y181C mutant using 17-mer DNA/Alexa Fluor 488 5'-end labeled DNA/Alexa Fluor 555-aha-dUTP as primer/template/substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50532848(CHEMBL4443785)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HIV1 RT V108I mutant using 17-mer DNA/Alexa Fluor 488 5'-end labeled DNA/Alexa Fluor 555-aha-dUTP as primer/template/substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50532848(CHEMBL4443785)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HIV1 RT V108I mutant using 17-mer DNA/Alexa Fluor 488 5'-end labeled DNA/Alexa Fluor 555-aha-dUTP as primer/template/substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed