BDBM50533680 CHEMBL4455068
SMILES NC(=O)c1cnc(Nc2ccccn2)cc1NC1CCN(CC1)c1ccc(cn1)C#N
InChI Key InChIKey=OGJWWUCDNHVDOY-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50533680
Affinity DataIC50: 4.90nMAssay Description:Inhibition of human JAK2 assessed as reduction in phosphorylation of Biotin-Lyn-Substrate-2 after 1 hr in presence of ATP by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 360nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells after 10 mins by Rb efflux assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human JAK1 assessed as reduction in phosphorylation of Biotin-Lyn-Substrate-2 after 1 hr in presence of ATP by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.460nMAssay Description:Inhibition of human JAK3 assessed as reduction in phosphorylation of Biotin-Lyn-Substrate-2 after 1 hr in presence of ATP by ELISAMore data for this Ligand-Target Pair