BDBM50534996 CHEMBL4528472
SMILES FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCN(CC1)C(=O)[C@H]1CCCCN1)N1CCOCC1
InChI Key InChIKey=FKKDALJRRYJPCE-GOSISDBHSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50534996
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of PI3Kdelta (unknown origin) expressed in baculovirus expression system by kinase-glo luminescence assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 3.59E+3nMAssay Description:Inhibition of PI3Kgamma (unknown origin) expressed in baculovirus expression system by kinase-glo luminescence assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 775nMAssay Description:Inhibition of PI3Kbeta (unknown origin) expressed in baculovirus expression system by kinase-glo luminescence assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of PI3Kdelta N836D mutant (unknown origin) expressed in Sf21 cells co-expressing p85 by kinase-glo luminescence assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 2.37E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) expressed in baculovirus expression system by kinase-glo luminescence assayMore data for this Ligand-Target Pair