BDBM50535031 CHEMBL4483334

SMILES OC(=O)c1cccc(c1)[C@H]1C[C@H](C[C@H](O1)c1ccccc1)NC(=O)C1(CC1)c1ccc2OC(F)(F)Oc2c1

InChI Key InChIKey=OOMFMAUDWWBORL-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50535031   

TargetCystic fibrosis transmembrane conductance regulator(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50535031(CHEMBL4483334)
Affinity DataEC50:  100nMAssay Description:Corrector activity at CFTR F508del mutant in human bronchial epithelial cells incubated for 18 to 24 hrs by TECC-based conductance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50535031(CHEMBL4483334)
Affinity DataEC50:  280nMAssay Description:Corrector activity at CFTR F508del mutant (unknown origin) expressed in human CFBE41o cells incubated for 18 to 24 hrs by CSE-HRP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed