BDBM50537426 CHEMBL4593058
SMILES COCCn1cc(Nc2cc(NCc3ccc(NC(=O)C=C)cc3)ncn2)cn1
InChI Key InChIKey=USASTERQYJIQNG-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50537426
Affinity DataIC50: 9.30nMAssay Description:Inhibition of human JAK3 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human TYK2 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair
Affinity DataIC50: 852nMAssay Description:Inhibition of human JAK1 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair