BDBM50538090 CHEMBL4648742

SMILES c1c(-c2ccncc2)c2ccncc2n1-c1ccccc1

InChI Key InChIKey=OJNWEVWJYCSDGV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50538090   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50538090(CHEMBL4648742)
Affinity DataIC50:  13nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DYRK1A (1 to 763 residues) expressed in Sf21 cells using Ulight-glycogen synthase as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50538090(CHEMBL4648742)
Affinity DataIC50: >3.00E+4nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in CHO cells incubated for 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50538090(CHEMBL4648742)
Affinity DataIC50: >8.30E+3nMAssay Description:Inhibition of recombinant human His/GST-tagged GSK3beta (2 to 433 residues) expressed in baculovirus infected Sf9 cells using Ulight-glycogen synthas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed