BDBM50538592 CHEMBL4646045

SMILES COc1cc2CCN(CCc3ccc(NC(=O)\C=C\c4ccc(Oc5cccc(c5)-c5ccccn5)nc4)cc3)Cc2cc1OC

InChI Key InChIKey=AJGWAABNSFMUOW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50538592   

TargetATP-dependent translocase ABCB1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50538592(CHEMBL4646045)
Affinity DataIC50: 750nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed