BDBM50539389 CHEMBL4636684

SMILES OC(=O)C(=C1\OC(=O)C(=C1O)c1ccc(O)c(O)c1)\c1ccc(O)c(O)c1

InChI Key InChIKey=MRRYHTCWZKZVIH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50539389   

TargetProtein kinase C beta type(Rat)
Tokyo University of Agriculture

Curated by ChEMBL
LigandPNGBDBM50539389(CHEMBL4636684)
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of PKCbeta in rat RBL2H3 cells assessed as inhibition of mouse anti-DNP IgE-stimulated beta-hexosaminidase release preincubated for 15 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Tokyo University of Agriculture

Curated by ChEMBL
LigandPNGBDBM50539389(CHEMBL4636684)
Affinity DataIC50: 1.68E+4nMAssay Description:Inhibition of PKCbeta in rat RBL2H3 cells assessed as inhibition of anti-DNP IgE-stimulated TNFalpha release preincubated for 15 mins followed by mou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Tokyo University of Agriculture

Curated by ChEMBL
LigandPNGBDBM50539389(CHEMBL4636684)
Affinity DataIC50: 2.01E+4nMAssay Description:Inhibition of PKCbeta in rat RBL2H3 cells assessed as inhibition of ionomycin-stimulated TNFalpha release preincubated for 15 mins followed by ionomy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Tokyo University of Agriculture

Curated by ChEMBL
LigandPNGBDBM50539389(CHEMBL4636684)
Affinity DataIC50: 2.22E+4nMAssay Description:Inhibition of PKCbeta in rat RBL2H3 cells assessed as inhibition of ionomycin-stimulated beta-hexosaminidase release preincubated for 15 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
Tokyo University of Agriculture

Curated by ChEMBL
LigandPNGBDBM50539389(CHEMBL4636684)
Affinity DataIC50: 3.62E+4nMAssay Description:Inhibition of recombinant full-length N-temrinal GST-tagged human PKC beta1 expressed in baculovirus infected Sf9 cells using TMB as substrate incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed