BDBM50539781 CHEMBL4647634

SMILES NC(=O)c1cccc(c1)-c1ccc2sc(NC(=O)c3ccc(F)cc3C(F)(F)F)nc2c1

InChI Key InChIKey=SVMFSEOXMIEWOX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50539781   

TargetProstaglandin E synthase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50539781(CHEMBL4647634)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of mPGES1 in human A549 cells assessed as reduction in IL-1beta induced PGE2 release using PGH2 as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed