BDBM50540594 CHEMBL4643145

SMILES Cc1ccc(CN2CCCN(CC2)C(=O)c2ccncc2)c(C)c1

InChI Key InChIKey=PJAULXQZQOWEPI-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50540594   

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50540594(CHEMBL4643145)
Affinity DataKi:  116nMAssay Description:Displacement of [3H]ifenprodil from GluN2B (unknown origin) expressed in mouse L(tk-) cell membranes co-expressing GluN1a incubated for 120 mins by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50540594(CHEMBL4643145)
Affinity DataKi:  254nMAssay Description:Displacement of [3H]-(+)pentazocine from sigma-1 receptor in guinea pig brain membranes after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50540594(CHEMBL4643145)
Affinity DataKi:  2.00E+3nMAssay Description:Displacement of [3H]-Di-o-tolylguanidine from sigma-2 receptor in rat liver membranes after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed