BDBM50540712 CHEMBL4634047

SMILES CC[C@H](C)[C@@H]1NC(=O)CNC(=O)[C@@H]2CCCN2C(=O)[C@@H](NC(=O)C(CCC(O)=O)NC(=O)[C@H](CC(N)=O)NC(=O)C(CC(N)=O)NC(=O)[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](NC(=O)[C@@H](N)CSSC[C@H](NC1=O)C(O)=O)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O

InChI Key InChIKey=XNITXKXGHLCMJT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50540712   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De Qu£Mica M£Dica (Iqm, Csic)

Curated by ChEMBL
LigandPNGBDBM50540712(CHEMBL4634047)
Affinity DataIC50: 1.37E+5nMAssay Description:Inhibition of HIV-1 reverse transcriptase His-tagged p51 heterodimerization with HIV-1 reverse transcriptase p66 incubated for 16 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De Qu£Mica M£Dica (Iqm, Csic)

Curated by ChEMBL
LigandPNGBDBM50540712(CHEMBL4634047)
Affinity DataIC50: 1.45E+5nMAssay Description:Inhibition of recombinant HIV-1 BH10 reverse transcriptase p51/p66 expressed in Escherichia coli preincubated for 10 mins followed by D38/25PGA templ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De Qu£Mica M£Dica (Iqm, Csic)

Curated by ChEMBL
LigandPNGBDBM50540712(CHEMBL4634047)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of recombinant HIV-1 BH10 reverse transcriptase p51/p66 expressed in Escherichia coli assessed as reduction in recovery of DNA polymerase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed