BDBM50540762 CHEMBL4638701
SMILES O=c1[nH]c(SCCN2CCN(CCSc3nc4ccccc4c(=O)[nH]3)CC2)nc2ccccc12
InChI Key InChIKey=RHCZTJJJLXGIDT-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50540762
Affinity DataIC50: 90nMAssay Description:Inhibition of full length human C-terminal His-tagged PARP1 expressed in baculovirus infected Sf9 cells using chicken core histone as substrate incub...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University of Naples
Curated by ChEMBL
University of Naples
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of full length human N-terminal GST-tagged TNKS2 ADP-ART catalytic domain (1001 to 1327 residues) using histone H2A as substrate incubated...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
University of Naples
Curated by ChEMBL
University of Naples
Curated by ChEMBL
Affinity DataIC50: 6.10nMAssay Description:Inhibition of full length human N-terminal GST-tagged TNKS1 ADP-ART catalytic domain (1001 to 1327 residues) using histone H2A as substrate incubated...More data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibition of full length human N-terminal His-tagged PARP2 expressed in baculovirus infected Sf9 cells using histone H3.3 as substrate incubated for...More data for this Ligand-Target Pair