BDBM50540805 CHEMBL4641719

SMILES Cc1cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c(C)n1-c1ccccc1

InChI Key InChIKey=RTVHEHWDLWSVKC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50540805   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50540805(CHEMBL4641719)
Affinity DataIC50: 5.78E+3nMAssay Description:Inhibition of human EZH2 using core histone as substrate incubated for 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50540805(CHEMBL4641719)
Affinity DataIC50: 1.54E+4nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed