BDBM50541163 CHEMBL4639024

SMILES CC(C)OP(=O)(OC(C)C)C(Cc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C)P(=O)(OC(C)C)OC(C)C

InChI Key InChIKey=YLJOVCWVJCDPLN-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50541163   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50541163(CHEMBL4639024)
Affinity DataEC50:  470nMAssay Description:Induction of human HMGCR-dCat-ELuc degradation expressed in HEK293 cells assessed as reduction in luciferase activity after 4 hrs by luciferase repor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50541163(CHEMBL4639024)
Affinity DataEC50:  876nMAssay Description:Induction of degradation of Flag-tagged human HMGCR-dCat-ELuc membrane domain (1 to 499 residues) expressed in HEK293 cells assessed as reduction in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50541163(CHEMBL4639024)
Affinity DataEC50:  880nMAssay Description:Induction of HMGCR degradation (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed