BDBM50541270 CHEMBL4645772

SMILES COc1cccc(Cn2ncc3cc(ccc3c2=O)-c2ccc3[nH]ncc3c2)c1

InChI Key InChIKey=IWPAOEBVWYFVID-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50541270   

TargetRho-associated protein kinase 2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50541270(CHEMBL4645772)
Affinity DataIC50: 398nMAssay Description:Inhibition of recombinant human ROCK2 (11 to 552 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50541270(CHEMBL4645772)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human ROCK1 (17 to 535 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed