BDBM50541291 CHEMBL4639553

SMILES Nc1cc(ccn1)-c1cc2c(ncn(Cc3cccc(c3)C(F)(F)F)c2=O)s1

InChI Key InChIKey=NVCOFSKWCYVDML-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50541291   

TargetRho-associated protein kinase 2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50541291(CHEMBL4639553)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human ROCK2 (11 to 552 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50541291(CHEMBL4639553)
Affinity DataIC50: 490nMAssay Description:Inhibition of recombinant human ROCK1 (17 to 535 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed