BDBM50541294 CHEMBL4649876

SMILES COc1cc(Cn2cnc3sc(cc3c2=O)-c2ccnc(N)c2)cc(OC)c1

InChI Key InChIKey=BSGMJKJCSAXOMH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50541294   

TargetRho-associated protein kinase 2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50541294(CHEMBL4649876)
Affinity DataIC50: 58nMAssay Description:Inhibition of recombinant human ROCK2 (11 to 552 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50541294(CHEMBL4649876)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human ROCK1 (17 to 535 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed