BDBM50541414 CHEMBL4634872

SMILES O=C(On1nnc2ccccc12)c1cc[nH]c1

InChI Key InChIKey=PNKVRKKJLPVSKP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50541414   

TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Engineering Research Center For The Development and Application of Ethnic Medicine and Tcm (Ministry of Education)

Curated by ChEMBL
LigandPNGBDBM50541414(CHEMBL4634872)
Affinity DataIC50: 5.66E+4nMAssay Description:Inhibition of SIRT2 deacetylation activity (unknown origin) using H3K9Ac ( 4 to 15 residues) as substrate by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Engineering Research Center For The Development and Application of Ethnic Medicine and Tcm (Ministry of Education)

Curated by ChEMBL
LigandPNGBDBM50541414(CHEMBL4634872)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of SIRT1 deacetylation activity (unknown origin) using H3K9Ac (4 to 15 residues) as substrate by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Engineering Research Center For The Development and Application of Ethnic Medicine and Tcm (Ministry of Education)

Curated by ChEMBL
LigandPNGBDBM50541414(CHEMBL4634872)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of SIRT3 deacetylation activity (unknown origin) using H3K9Ac (4 to 15 residues) as substrate by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Engineering Research Center For The Development and Application of Ethnic Medicine and Tcm (Ministry of Education)

Curated by ChEMBL
LigandPNGBDBM50541414(CHEMBL4634872)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of SIRT5 desuccinylation activity (unknown origin) using H3K9Su (4 to 15 residues) as substrate by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed