BDBM50541416 CHEMBL4643733

SMILES O=C(On1nnc2ccccc12)c1c[nH]c2ccccc12

InChI Key InChIKey=ZUICDDCLDBHMCH-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50541416   

TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Engineering Research Center For The Development and Application of Ethnic Medicine and Tcm (Ministry of Education)

Curated by ChEMBL
LigandPNGBDBM50541416(CHEMBL4643733)
Affinity DataIC50: 1.43E+4nMAssay Description:Inhibition of SIRT2 deacetylation activity (unknown origin) using H3K9Ac ( 4 to 15 residues) as substrate by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Engineering Research Center For The Development and Application of Ethnic Medicine and Tcm (Ministry of Education)

Curated by ChEMBL
LigandPNGBDBM50541416(CHEMBL4643733)
Affinity DataIC50: 2.21E+4nMAssay Description:Inhibition of SIRT2 deacetylation activity (unknown origin) using H4K8Ac (3 to 13 residues) as substrate by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Engineering Research Center For The Development and Application of Ethnic Medicine and Tcm (Ministry of Education)

Curated by ChEMBL
LigandPNGBDBM50541416(CHEMBL4643733)
Affinity DataIC50: 7.36E+4nMAssay Description:Inhibition of SIRT2 defatty-acylation activity (unknown origin) using H4K8-Myr (3 to 13 residues) as substrate by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Engineering Research Center For The Development and Application of Ethnic Medicine and Tcm (Ministry of Education)

Curated by ChEMBL
LigandPNGBDBM50541416(CHEMBL4643733)
Affinity DataIC50: 8.10E+4nMAssay Description:Inhibition of SIRT2 debenzoylation activity (unknown origin) using benzoylated histone H4K8 peptide (3 to 13 residues ) as substrate by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Engineering Research Center For The Development and Application of Ethnic Medicine and Tcm (Ministry of Education)

Curated by ChEMBL
LigandPNGBDBM50541416(CHEMBL4643733)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of SIRT3 deacetylation activity (unknown origin) using H3K9Ac (4 to 15 residues) as substrate by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Engineering Research Center For The Development and Application of Ethnic Medicine and Tcm (Ministry of Education)

Curated by ChEMBL
LigandPNGBDBM50541416(CHEMBL4643733)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of SIRT5 desuccinylation activity (unknown origin) using H3K9Su (4 to 15 residues) as substrate by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Engineering Research Center For The Development and Application of Ethnic Medicine and Tcm (Ministry of Education)

Curated by ChEMBL
LigandPNGBDBM50541416(CHEMBL4643733)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of SIRT1 deacetylation activity (unknown origin) using H3K9Ac (4 to 15 residues) as substrate by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed