BDBM50541418 CHEMBL4640752

SMILES Brc1ccc2[nH]cc(C(=O)On3nnc4ncccc34)c2c1

InChI Key InChIKey=XLDVXYDNCAZWFP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50541418   

TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Engineering Research Center For The Development and Application of Ethnic Medicine and Tcm (Ministry of Education)

Curated by ChEMBL
LigandPNGBDBM50541418(CHEMBL4640752)
Affinity DataIC50: 4.03E+4nMAssay Description:Inhibition of SIRT1 deacetylation activity (unknown origin) using H3K9Ac (4 to 15 residues) as substrate by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Engineering Research Center For The Development and Application of Ethnic Medicine and Tcm (Ministry of Education)

Curated by ChEMBL
LigandPNGBDBM50541418(CHEMBL4640752)
Affinity DataIC50: 6.70E+4nMAssay Description:Inhibition of SIRT3 deacetylation activity (unknown origin) using H3K9Ac (4 to 15 residues) as substrate by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Engineering Research Center For The Development and Application of Ethnic Medicine and Tcm (Ministry of Education)

Curated by ChEMBL
LigandPNGBDBM50541418(CHEMBL4640752)
Affinity DataIC50: 7.71E+4nMAssay Description:Inhibition of SIRT2 deacetylation activity (unknown origin) using H3K9Ac ( 4 to 15 residues) as substrate by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Engineering Research Center For The Development and Application of Ethnic Medicine and Tcm (Ministry of Education)

Curated by ChEMBL
LigandPNGBDBM50541418(CHEMBL4640752)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of SIRT5 desuccinylation activity (unknown origin) using H3K9Su (4 to 15 residues) as substrate by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed