BDBM50541786 CHEMBL4647543

SMILES CCS(=O)(=O)N1CC(C1)Oc1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C

InChI Key InChIKey=SJINSMXRIOLHPI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50541786   

LigandPNGBDBM50541786(CHEMBL4647543)
Affinity DataIC50: 1nMAssay Description:Inhibition of CYP11B2 in HEK293 cell assessed as reduction in 18-hyroxycorticosterone by LC/MS-MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
LigandPNGBDBM50541786(CHEMBL4647543)
Affinity DataIC50: 1nMAssay Description:Inhibition of CYP11B2 in HEK293 cell assessed as reduction in aldosterone by LC/MS-MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
LigandPNGBDBM50541786(CHEMBL4647543)
Affinity DataIC50: 4nMAssay Description:Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed