BDBM50541959 CHEMBL4649188

SMILES FC(F)(F)c1coc(NC(=O)CCc2ccc(OCc3ccccc3)cc2)n1

InChI Key InChIKey=FAYKWAQYWCIDKM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50541959   

TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University

Curated by ChEMBL
LigandPNGBDBM50541959(CHEMBL4649188)
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant human full length sEH (1 to 555 residues) expressed in Escherichia coli BL21 DE3 cells assessed as reduction in 6-methoxyna...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University

Curated by ChEMBL
LigandPNGBDBM50541959(CHEMBL4649188)
Affinity DataIC50: 320nMAssay Description:Inhibition of full-length human sEH (1 to 555 residues) expressed in Escherichia coli BL21 (DE3) using PHOME as substrate preincubated for 45 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Goethe-University

Curated by ChEMBL
LigandPNGBDBM50541959(CHEMBL4649188)
Affinity DataIC50: 570nMAssay Description:Inhibition of recombinant human full length C-terminal His6-tagged LTA4H expressed in Escherichia coli BL21 DE3 cells assessed as reduction in amino-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Goethe-University

Curated by ChEMBL
LigandPNGBDBM50541959(CHEMBL4649188)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of C-terminal Hexahistidine-tagged recombinant human LTAH4 expressed in Escherichia coli BL21 (DE3) using L-arginine-7-amino-4-methylcouma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed