BDBM50542174 CHEMBL4632427

SMILES CCOC(=O)C1=C(C)Nc2nc3ccccc3n2C1c1ncc[nH]1

InChI Key InChIKey=UZFAUIPNCCEZOK-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50542174   

TargetAdenosine receptor A2a(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50542174(CHEMBL4632427)
Affinity DataKi:  5nMAssay Description:Displacement [3H]ZM241385 from adenosine A2A receptor in human HeLa cell membranes incubated for 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50542174(CHEMBL4632427)
Affinity DataKi:  402nMAssay Description:Displacement [3H]DPCPX from human adenosine A2B receptor expressed in HEK293 cell membranes incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50542174(CHEMBL4632427)
Affinity DataIC50: 4.54E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin) expressed in insect cell microsomes using dibenzylfluorescein substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed