BDBM50542570 CHEMBL4647298

SMILES FC(F)(F)CCNc1nccn2c(cnc12)-c1ccc(cc1)C(=O)NC1CC1

InChI Key InChIKey=ONMCQVFQANHXPX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50542570   

TargetDual specificity protein kinase TTK(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50542570(CHEMBL4647298)
Affinity DataIC50: 5nMAssay Description:Inhibition of GST-tagged recombinant human MPS1 expressed in baculovirus expression system using biotin-Ahx-PWDPDDADITEILG as substrate preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50542570(CHEMBL4647298)
Affinity DataIC50: 5nMAssay Description:Inhibition of human MPS1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDual specificity protein kinase TTK(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50542570(CHEMBL4647298)
Affinity DataIC50: 174nMAssay Description:Inhibition of GST-tagged recombinant human MPS1 expressed in baculovirus expression system using biotin-Ahx-PWDPDDADITEILG as substrate preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed