BDBM50542579 CHEMBL4649817

SMILES CC(C)CNc1nc(cn2c(cnc12)-c1ccc(cc1)C(=O)NC1CC1)-c1ccccc1

InChI Key InChIKey=QGCHHJBTBVGDDZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50542579   

TargetDual specificity protein kinase TTK(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50542579(CHEMBL4649817)
Affinity DataIC50: 2nMAssay Description:Inhibition of GST-tagged recombinant human MPS1 expressed in baculovirus expression system using biotin-Ahx-PWDPDDADITEILG as substrate preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50542579(CHEMBL4649817)
Affinity DataIC50: 61nMAssay Description:Inhibition of GST-tagged recombinant human MPS1 expressed in baculovirus expression system using biotin-Ahx-PWDPDDADITEILG as substrate preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed