BDBM50542845 CHEMBL4646733

SMILES CC(C)C[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O

InChI Key InChIKey=DSABUOKTPFOKMP-UHFFFAOYSA-N

Data  8 KI  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50542845   

TargetNeuropeptide Y receptor type 4(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50542845(CHEMBL4646733)
Affinity DataKi:  8.70nMAssay Description:Displacement of [3H]UR-KK200 from human Y4 receptor expressed in CHO cells co-expressing Gqi5-mtAEQ measured after 90 mins by scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 4(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50542845(CHEMBL4646733)
Affinity DataKi:  8.90nMAssay Description:Displacement of [3H]UR-KK200 from human Y4 receptor expressed in CHO cells co-expressing Gqi5-mtAEQ measured after 90 mins by scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 4(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50542845(CHEMBL4646733)
Affinity DataEC50:  316nMAssay Description:Agonist activity at human Y4R expressed in HEK293T cells co-expressing ARRB2 assessed as induction of beta-arrestin2 recruitment measured for 40 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 4(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50542845(CHEMBL4646733)
Affinity DataEC50:  320nMAssay Description:Agonist activity at human Y4R expressed in HEK293T cells co-expressing ARRB2 assessed as induction of beta-arrestin2 recruitment measured for 40 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 4(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50542845(CHEMBL4646733)
Affinity DataEC50:  550nMAssay Description:Agonist activity at human Y4R expressed in HEK293T cells co-expressing ARRB1 assessed as induction of beta-arrestin1 recruitment measured for 40 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 4(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50542845(CHEMBL4646733)
Affinity DataEC50:  550nMAssay Description:Agonist activity at human Y4 receptor expressed in CHO cells co-expressing Gqi5-mtAEQ assessed as intracellular calcium mobilization measured for 43 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 4(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50542845(CHEMBL4646733)
Affinity DataEC50:  550nMAssay Description:Agonist activity at human Y4 receptor expressed in CHO cells co-expressing Gqi5-mtAEQ assessed as intracellular calcium mobilization measured for 43 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 4(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50542845(CHEMBL4646733)
Affinity DataEC50:  550nMAssay Description:Agonist activity at human Y4R expressed in HEK293T cells co-expressing ARRB1 assessed as induction of beta-arrestin1 recruitment measured for 40 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50542845(CHEMBL4646733)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]propionyl-pNPY from human Y5 receptor expressed in human HEC1B cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50542845(CHEMBL4646733)
Affinity DataKi: <1.00E+3nMAssay Description:Displacement of [3H]propionyl-pNPY from human Y5 receptor expressed in human HEC1B cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50542845(CHEMBL4646733)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]UR-MK299 from Y1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50542845(CHEMBL4646733)
Affinity DataKi: <1.00E+3nMAssay Description:Displacement of [3H]UR-MK299 from Y1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50542845(CHEMBL4646733)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]propionyl-pNPY from human Y2 receptor expressed in CHO cells measured after 2 hrs by microbeta liquid scintillation counting anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50542845(CHEMBL4646733)
Affinity DataKi: <1.00E+4nMAssay Description:Displacement of [3H]propionyl-pNPY from human Y2 receptor expressed in CHO cells measured after 2 hrs by microbeta liquid scintillation counting anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed