BDBM50543107 CHEMBL4633346

SMILES CC(=N)Nc1ccc(cc1)C(=O)Nc1ccc(F)cc1

InChI Key InChIKey=UZYBSCMHYZNRFS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50543107   

TargetNitric oxide synthase, inducible(Human)
University "G. D'Annunzio" of Chieti-Pescara

Curated by ChEMBL
LigandPNGBDBM50543107(CHEMBL4633346)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant N-terminal His-tagged human iNOS expressed in Escherichia coli using L-arginine as substrate preincubated for 15 mins follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
University "G. D'Annunzio" of Chieti-Pescara

Curated by ChEMBL
LigandPNGBDBM50543107(CHEMBL4633346)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of recombinant human nNOS expressed in Escherichia coli using L-arginine as substrate preincubated for 15 mins followed by NADPH addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
University "G. D'Annunzio" of Chieti-Pescara

Curated by ChEMBL
LigandPNGBDBM50543107(CHEMBL4633346)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human eNOS using L-argininge as substrate preincubated for 15 mins followed by NADPH addition and measured after 20 mins by OPA/NAC rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed