BDBM50543403 CHEMBL4642678

SMILES Oc1cccc2cc(C(=O)Nc3ccccc3F)c(=N)oc12

InChI Key InChIKey=ZMNXHPLQWYRJBV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50543403   

TargetAldo-keto reductase family 1 member C3(Human)
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50543403(CHEMBL4642678)
Affinity DataIC50: 64nMAssay Description:Inhibition of recombinant AKR1C3 (unknown origin) assessed as reduction in S-tetralol-induced dehydrogenase activity by measuring NADPH levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50543403(CHEMBL4642678)
Affinity DataIC50: 4.40E+3nMAssay Description:Antagonistic activity at AR in human 22Rv1 cells assessed as reduction in cell number by CCK8 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed